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Related Experiment Videos

How gene families evolve.

T Ohta1

  • 1National Institute of Genetics, Mishima, Japan.

Theoretical Population Biology
|February 1, 1990
PubMed
Summary
This summary is machine-generated.

Gene families evolve through concerted evolution, with rates adjusted over time. Some families develop into superfamilies, where members gain unique, essential functions, like the homeobox gene family.

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Area of Science:

  • Evolutionary biology
  • Genetics

Background:

  • Gene families exhibit diverse structures, from uniform to varied.
  • Concerted evolution is a common mechanism for ancient gene families.

Purpose of the Study:

  • To review theories and facts of gene family evolution.
  • To explore the transition of gene families into superfamilies.

Main Methods:

  • Review of existing literature on gene family evolution.
  • Analysis of homogenization mechanisms like unequal crossing-over and gene conversion.

Main Results:

  • Homogenization rates are evolutionarily tuned for each gene family.
  • Gene families can evolve into superfamilies, losing concerted evolution.

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  • Superfamily members acquire distinct, indispensable functions.

    • Conclusions:

    • The evolution of gene families is a dynamic process.
    • Superfamily formation allows for functional diversification and specialization.
    • The homeobox gene family serves as a key example of superfamily evolution.