Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Long-term response to artificial selection with multiple alleles--study by simulations.

Z B Zeng1, C C Cockerham

  • 1Department of Statistics, North Carolina State University, Raleigh 27695-8203.

Theoretical Population Biology
|February 1, 1990
PubMed
Summary

Multiple alleles have minor effects on selection response ratios and half-life under neutral initial frequencies, but significantly impact response variance. Equal initial frequencies show increased response ratios and half-lives with more alleles.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Random and fixed effects in plant genetics.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same author

Covariances of relatives and selection response in generations of selfing from an outcrossed base population.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same author

Mixture model equations for marker-assisted genetic evaluation.

Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie·2005
Same author

An analysis of polygenes affecting wing shape on chromosome 2 in Drosophila melanogaster.

Genetics·2001
Same author

A multivalent pairing model of linkage analysis in autotetraploids.

Genetics·2001
Same author

A general polyploid model for analyzing gene segregation in outcrossing tetraploid species.

Genetics·2001

Area of Science:

  • Quantitative genetics
  • Population genetics
  • Evolutionary biology

Background:

  • Understanding long-term selection response is crucial in quantitative genetics.
  • The influence of multiple alleles on selection dynamics requires detailed investigation.

Purpose of the Study:

  • To examine the impact of multiple alleles on long-term selection response.
  • To analyze how allele number and selection intensity affect selection response properties.

Main Methods:

  • Simulations using a pseudosampling technique to model multidimensional diffusion.
  • Allele effects drawn from a normal distribution.
  • Two initial gene frequency distributions: equal and neutral equilibrium.

Main Results:

Related Experiment Videos

  • Under neutral initial frequencies, multiple alleles have minor effects on response ratios and half-life but significant effects on response variance.
  • Under equal initial frequencies, multiple alleles increase response ratios and half-life.
  • Selection intensity can increase the variance of the selection limit under certain conditions.

Conclusions:

  • The effects of multiple alleles on selection response can be minimized by parameter transformations for specific initial gene frequencies.
  • These effects cannot be universally removed by a single transformation or reparameterization.