Experience of pediatric stroke from a tertiary medical center in North India

Jayantee Kalita1, Gourav Goyal, Usha Kant Misra

  • 1Department of Neurology, Sanjay Gandhi Post Graduate Medical Sciences, Lucknow, India.

Insights

Pediatric stroke in Northern India is most commonly arterial ischemic stroke (AIS), often caused by infections. Level of consciousness on admission predicted mortality in these stroke cases.

Area of Science:

  • Neurology
  • Pediatrics
  • Public Health

Background:

  • Pediatric stroke etiology and outcomes vary globally.
  • Limited comprehensive data exists for pediatric stroke in India.
  • This study addresses the gap by analyzing cases from Northern India.

Purpose of the Study:

  • To evaluate the causes, types, and outcome predictors of pediatric stroke in Northern India.
  • To provide region-specific data on pediatric stroke epidemiology.

Main Methods:

  • Retrospective analysis of 79 pediatric stroke patients (1 month to 18 years) from 2001-2011.
  • Data collected included clinical, imaging, laboratory findings, and stroke risk factors.
  • Multivariate analysis identified predictors of mortality.

Main Results:

  • Arterial ischemic stroke (AIS) was the most common type (78.5%), followed by intracerebral hemorrhage (ICH) (12.7%) and cerebral venous sinus thrombosis (CVST) (8.9%).
  • Neuroinfections were the leading cause (31.6%), followed by cardioembolic sources (11.4%) and cryptogenic strokes (16.5%).
  • Mortality was 8.9%, with the level of consciousness on admission identified as a significant predictor of death.

Conclusions:

  • AIS is more prevalent than ICH in this Northern Indian cohort.
  • Infections represent a significant and potentially preventable cause of pediatric stroke in the region.
  • Early assessment of consciousness level is crucial for predicting outcomes in pediatric stroke.
Abstract

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