Related Experiment Video
Updated: May 15, 2026
08:26
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
[Perforation associated with colorectal cancer]
Shigeru Fujisaki1, Motoi Takashina, Kenichi Sakurai
1Dept. of Surgery, Fujisaki Hospital, Japan.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|December 27, 2012
Summary
Surgery for perforated colorectal cancer involves removing the tumor and perforation site. Aggressive sepsis management and definitive oncologic surgery are crucial for long-term survival in these complex cases.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Colorectal Surgery
Context:
- Perforation associated with colorectal cancer presents unique surgical challenges.
- Understanding the location and cause of perforation is critical for treatment planning.
- Locally advanced disease and peritoneal dissemination are common in cases of tumor perforation.
Purpose:
- To evaluate the surgical management and outcomes of patients with perforated colorectal cancer.
- To identify factors influencing short-term and long-term survival.
Summary:
- This study analyzed 13 patients with perforated colorectal cancer, with most primary tumors located in the rectum or sigmoid colon.
- Perforations occurred either at the tumor site (often locally advanced) or proximal to it, causing complications like obstructive colitis.
- Surgical intervention included resection of the primary tumor and perforation site in most cases, with a 15.4% 30-day mortality rate.
- Long-term survival (over 2 years) was achieved in 6 patients, highlighting the importance of both sepsis control and oncologic resection.
Impact:
- The findings underscore the necessity of a combined approach, managing sepsis and performing definitive oncologic surgery, for improved outcomes in perforated colorectal cancer.
- This research informs surgical strategies for perforated colorectal cancer, aiming to enhance patient survival and reduce recurrence rates.
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