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[Preliminary study on chemical constituents seperated from Cayratia japonica]
Chuan-wen Cui1, Cui-ling Sun, Quan-cheng Chen
1School of Pharmaceutical Sciences, Xiamen University, Xiamen 361005, China.
Objective:
To study effective active constituents of Cayratia japonica,a genuine herbal medicine from Fujian.
Method:
Such chromatographic methods as Macroporous, Sephadex LH-20, ODS and normal phase silica gel column chromatography were adopted to separate the chemical components of C. japonica.
Result:
Thirteen compounds were obtained, and their structures were identified by analyzing multiple spectral data as luteolin(1), apigenin(2), triethyl citrate-(3), 3-formylindole(4), esculetin(5), bis(2-ethylhexyl)-phthalate(6), calendin(7), ethyl-trans-3,4-dihydr-oxycinnamate(8), luteolin7-O-D-glucoside(9),5-hydroxy-3,4-dimethyl-5-pentyl-2(5H-furanone(10),ethyl-3,4-dihydroxybenzoate(11), eriodictyol(12) and daucosterol(13).
Conclusion:
Among them, compounds 3-8 and 10-12 were separated from the plant for the first time.
