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[Design technology of traditional Chinese medicine component and formulation]
Dan-hong Yu1, Dan Liu, Zheng-hai Zhang
1Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China. xiaoyu9456@sina.com
Abstract:
The development of traditional Chinese medicine lies in its significant clinical efficacy which is closely related to the bioavailability of drugs. The nature of the material foundation of compounds of traditional Chinese medicine is reflected in multi-component. As for the nature of components themselves, the level of their bioavailability depends on the biopharmaceutical properties, namely solubility and permeability, to a great extent. Therefore, under the guidance of the theory of traditional Chinese medicine and in the combination with modern preparation techniques, this essay reveals key techniques capable of improving the biopharmaceutical properties of components, in the hope of enhancing the clinical efficacy of components of traditional Chinese medicine.
