Related Experiment Video
Updated: May 15, 2026

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
Published on: May 23, 2020
Early functional treatment in Class II division 1 subjects with mandibular retrognathia using Fränkel II appliance.
A Silvestrini-Biavati1, G Alberti, F Silvestrini Biavati
1Department of Orthodontics, DISC, University of Genoa, Italy. armando.silvestrini@tin.it
Aim:
This was to clarify dentoalveolar, skeletal and facial profile modifications induced by Fränkel II functional treatment in Class II division 1 subjects in prepubertal stages CS1-2.
Materials And Methods:
Evaluation of 25 caucasian subjects (15 males, 10 females), mean age 8y 11m, in vertebral stages CS1-2. The mean duration of functional treatment was 1y 11m.
Study Design:
Prospective controlled study. The sample was evaluated at T0, start of treatment, and T1, end of Fränkel II therapy. Untreated subjects in Class II division 1 were the control group.
Statistics:
T-test for paired data was calculated before and after treatment (P< 0.05).
Results:
A statistically significant increase between T0 and T1 was obtained for SNB (p = 0.022), ANB (p <0.001), Mx/Mn differential (p = 0.001), Co-Go-Me (p = 0.014), OJ (p < 0.001), OB (p = 0.042), IMPA (p = 0.021) . OJ (p < 0.001) and OB (p = 0.003) showed a higher significant change in the Fränkel group compared to control group.
Conclusion:
The Fränkel II appliance produced, in CS1-2 subiects, significant effects in teeth position, skeletal modifications and soft tissue changes, although the pubertal growth spurt would occur at least two years later.

