Children intoxications: what is abuse and what is not abuse

Ricardo Jorge Dinis-Oliveira1, Teresa Magalhães

  • 1Department of Legal Medicine and Forensic Sciences, Faculty of Medicine, University of Porto, Porto, Portugal. ricardinis@sapo.pt

Trauma, Violence & Abuse
|December 29, 2012
PubMed

Insights

Children are at high risk for poisoning due to exploration. This study addresses child poisoning, including abuse, and proposes protocols for professionals to minimize risks.

Area of Science:

  • Forensic Toxicology
  • Pediatric Health
  • Child Abuse Prevention

Background:

  • Young children's natural curiosity increases their risk of poisoning compared to older individuals.
  • Child poisoning is a significant cause of morbidity and mortality from age one through adulthood.
  • Poisoning is a common method of child abuse, resulting in numerous fatalities.

Purpose of the Study:

  • To alert health, forensic, and law enforcement professionals to the prevalence of child poisoning and abuse.
  • To demystify the misconception that child poisoning is a rare form of abuse or neglect.
  • To review xenobiotics and endobiotics involved in child intoxications and propose risk-minimization strategies.

Main Methods:

  • Review of xenobiotics (foreign compounds) and endobiotics (internal compounds) in child intoxications.
  • Discussion of historical, clinical, and toxicological evaluations for poisoning cases.
  • Proposal of harmonized protocols for sample collection in forensic toxicological analysis.

Main Results:

  • Children's vulnerability to high doses of xenobiotics and endobiotics necessitates specific considerations.
  • Contextual examples of exposure are provided to illustrate poisoning scenarios.
  • Emphasis on preparing children's environments to minimize poisoning risks.

Conclusions:

  • Harmonized protocols for sample collection and forensic analysis are crucial for addressing child poisoning.
  • Raising awareness among professionals is key to recognizing and managing child poisoning and abuse.
  • Environmental preparation and understanding toxicological concepts are vital for child safety.

Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Toxicity: Overview01:00

Drug Toxicity: Overview

Drug toxicity quantifies the harm a compound causes to an organism, varying by dose and potentially impacting whole systems or specific organs like the liver. Toxic reactions may arise from venomous insect or spider bites, with effects ranging from mild symptoms to severe outcomes such as brain damage or death. Common forms of acute poisoning include ethanol intoxication and overdose of pain or fever medications, with substances like GHB and heroin being particularly lethal at doses close to...
Drug Toxicity: Dose-Dependent Reactions01:24

Drug Toxicity: Dose-Dependent Reactions

Drug toxicities can be stratified into pharmacological, pathological, or genotoxic based on their mechanisms. The incidence and severity of these toxicities generally increase with the drug's concentration in the body and exposure time.Pharmacological toxicity is evident when the therapeutic effects of drugs overshoot into adverse reactions in a predictable, dose-dependent manner. Central nervous system (CNS) depression from barbiturates is a classic example, with effects escalating from...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...