Volitional control of neuromagnetic coherence
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Updated: May 15, 2026

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
Published on: May 8, 2021
Matthew D Sacchet1, Jürgen Mellinger, Ranganatha Sitaram
1Neurosciences Program, Stanford University School of Medicine Stanford, CA, USA ; Department of Psychology, Stanford University Stanford, CA, USA ; Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen Tübingen, Germany.
Abstract:
Coherence of neural activity between circumscribed brain regions has been implicated as an indicator of intracerebral communication in various cognitive processes. While neural activity can be volitionally controlled with neurofeedback, the volitional control of coherence has not yet been explored. Learned volitional control of coherence could elucidate mechanisms of associations between cortical areas and its cognitive correlates and may have clinical implications. Neural coherence may also provide a signal for brain-computer interfaces (BCI). In the present study we used the Weighted Overlapping Segment Averaging method to assess coherence between bilateral magnetoencephalograph sensors during voluntary digit movement as a basis for BCI control. Participants controlled an onscreen cursor, with a success rate of 124 of 180 (68.9%, sign-test p < 0.001) and 84 out of 100 (84%, sign-test p < 0.001). The present findings suggest that neural coherence may be volitionally controlled and may have specific behavioral correlates.
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