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Updated: May 15, 2026
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Published on: July 16, 2020
Habib EndoHPB: a novel endobiliary radiofrequency ablation device. An experimental study
Dimitris Zacharoulis1, Olga Lazoura, Eleni Sioka
1Department of Surgery, University Hospital of Larissa, Larissa, Greece. zachadim@yahoo.com
Background:
The Habib EndoHPB is a bipolar radiofrequency (RF) catheter developed to be introduced across malignant strictures of the bile ducts, so that RF energy can locally ablate the tumor prior to stent placement. This experiment aims to assess the ability of the catheter to coagulate the wall of the common bile duct (CBD) in a porcine model, to establish power requirement and time parameters and correlate them to the depth of thermal injury, and to assess the ease of operation of the device.
Methods:
The CBD was catheterized using the device in 20 pigs. RF energy was applied to the CBD wall with various generator settings. The pigs were sacrificed 24 hr after the application and the CBD was excised for histological analysis.
Results:
The device was easy to handle. Statistically significant correlations between the power, the time of RF application, and the thermal injury depth were found.
Conclusion:
The Habib EndoHPB catheter can effectively deliver RF energy intraluminally in the porcine CBD. Clinical studies are warranted in order to define proper settings for safe and efficient use in malignant biliary obstruction.
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