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Related Concept Videos

Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
Panic Disorder01:27

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
Anxiety: Overview01:18

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Anxiolytic Drugs: Benzodiazepines and Buspirone01:29

Anxiolytic Drugs: Benzodiazepines and Buspirone

Benzodiazepines are a class of anxiolytic drugs known for their rapid efficacy and high therapeutic-to-lethal dose ratio, but with a potential risk of drug dependence. These drugs are lipophilic, allowing for rapid absorption after oral administration, eventually reaching the central nervous system (CNS). Once in the CNS, benzodiazepines bind to the allosteric site of the GABAA receptor. This binding enhances the inhibitory effects of the neurotransmitter GABA. By doing so, they prevent...
Anxiolytic Drugs: Overview01:26

Anxiolytic Drugs: Overview

Anxiolytic drugs are vital in managing anxiety disorders by effectively alleviating symptoms such as excessive fear, tachycardia, and tremors. There are several classes of anxiolytic medications, each with unique mechanisms of action and potential side effects.
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic circuitry.
Social Anxiety Disorder01:28

Social Anxiety Disorder

Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.

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Related Experiment Video

Updated: May 15, 2026

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat
11:18

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat

Published on: September 12, 2014

Panic attacks in generalized anxiety disorder.

Michael Van Ameringen1, William Simpson, Beth Patterson

  • 1Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Canada. vanamer@mcmaster.ca

The Journal of Nervous and Mental Disease
|January 1, 2013
PubMed
Summary
This summary is machine-generated.

One in five patients with generalized anxiety disorder (GAD) experience panic attacks linked to catastrophic worry. These GAD panic attacks were more common in individuals with higher anxiety sensitivity, though other factors showed no significant differences.

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Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat
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Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat

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Reducing State Anxiety Using Working Memory Maintenance
08:17

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Anxiety Disorders Research

Background:

  • Generalized anxiety disorder (GAD) is often associated with worry.
  • Panic attacks can occur in GAD patients, particularly in response to catastrophic worry.
  • The specific characteristics and prevalence of GAD-related panic attacks are not well-defined in existing literature.

Purpose of the Study:

  • To investigate the prevalence of panic attacks in patients diagnosed with generalized anxiety disorder (GAD).
  • To characterize the types of panic attacks experienced by GAD patients.
  • To explore potential correlates of GAD panic attacks, including comorbidities, symptom severity, demographics, and family history.

Main Methods:

  • Retrospective chart evaluation of 254 patients diagnosed with DSM-IV Generalized Anxiety Disorder (GAD).
  • Assessment of the presence and specific types of panic attacks experienced by patients.
  • Analysis of demographic variables, family history, baseline symptom severity, and comorbidity as potential correlates.

Main Results:

  • Approximately 21% of patients with GAD reported experiencing GAD panic attacks.
  • The study identified varying percentages for different panic attack types: 21.7% situationally predisposed, 15.6% situationally bound, and 39.4% unexpected.
  • Patients with GAD panic attacks exhibited higher scores on the Anxiety Sensitivity Index compared to those with other panic attack types, but no other significant differences in evaluated correlates were found.

Conclusions:

  • One in five patients with GAD experience panic attacks associated with catastrophic worry.
  • Higher anxiety sensitivity may be a distinguishing feature for GAD panic attacks.
  • Further research and replication are necessary to validate these findings and fully understand GAD panic attacks.