Related Experiment Video
Updated: May 15, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
Smoking and mortality among persons aged 75-94
1The Herczeg Institute on Aging, Tel-Aviv University, Israel. Jiska@post.tau.ac.il
Objectives:
Examine the effect of current level of smoking and lifetime tobacco consumption on mortality in persons 75-94 years of age.
Methods:
Data were from a representative sample of older Jewish persons in Israel, which included 1,200 self-respondent participants aged 75-94 (Mean=83.1, SD=5.3) from the Cross-Sectional and Longitudinal Aging Study (CALAS). Data collection took place during 1989-1992. Mortality data on 95.1% of the sample at 20-year follow up were recorded from the Israeli National Population Registry.
Results:
The following variables adversely affected mortality for the whole sample: Smoking 11-20 cigarettes daily (HR=1.276, p<.05), smoking over 20 cigarettes daily (HR=1.328, p<.05), total tobacco consumption (HR=1.002, p<.01), and heavy lifetime tobacco consumption (HR=1.270, p<.01). Results were similar for persons aged 75-84, but the effect of smoking seems to decrease or disappear for ages 85 and above.
Conclusion:
This is the first report of all-cause mortality risk in both genders of a representative population aged 75 and over. Increased mortality risk is related to high daily quantity of current smoking, and to cumulative amount of lifetime smoking. The effect of smoking may disappear for ages 85 and above, and should be studied in larger oldest-old samples.
More Related Videos
10:47Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
Published on: February 21, 2011
08:40Optimization of the Wound Scratch Assay to Detect Changes in Murine Mesenchymal Stromal Cell Migration After Damage by Soluble Cigarette Smoke Extract
Published on: December 3, 2015
Related Concept Videos
Statistical Methods for Analyzing Epidemiological Data
Pharmacodynamics in Geriatric Patients: Effects of Age
Stress Prevention and Stress Management Techniques IV
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism