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Updated: May 15, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Hip-implant related chorio-retinal cobalt toxicity
Soo K Ng1, Andreas Ebneter, Jagjit S Gilhotra
1Department of Ophthalmology, South Australian Institute of Ophthalmology, Level 8, East Wing Royal Adelaide Hospital, North Terrace, Adelaide, South Australia.
Abstract:
A 39-year-old female with elevated serum cobalt levels from her bilateral hip prostheses presented with a 3-week history of blurred vision in her left eye. Optical coherence tomography revealed patchy degeneration of the photoreceptor-retinal pigment epithelium (RPE) complex. The lesions were hypofluorescent on indocyanine green angiography. We postulate that this is a case of implant-related chorio-retinal cobalt toxicity.
