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Updated: May 15, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
Aromatic-aromatic interactions in structures of proteins and protein-DNA complexes: a study based on orientation and
Ramnath Anjana1, Marthandan Kirti Vaishnavi, Durairaj Sherlin
1Supercomputer Education and Research Centre, Indian Institute of Science, Bangalore 560012, India.
Abstract:
Interactions between the aromatic amino acid residues have a significant influence on the protein structures and protein-DNA complexes. These interactions individually provide little stability to the structure; however, together they contribute significantly to the conformational stability of the protein structure. In this study, we focus on the four aromatic amino acid residues and their interactions with one another and their individual interactions with the four nucleotide bases. These are analyzed in order to determine the extent to which their orientation and the number of interactions contribute to the protein and protein-DNA complex structures.
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