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Updated: May 15, 2026

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
Published on: August 12, 2017
Interleukin-2 determinations for monitoring the renal allograft
U T Seyfert1, W Gumbel, H Berger
1Abt. für Klin. Hämostaseologie und Transfusionsmedizin der Unikliniken Homburg, Saar.
Abstract:
Our results show that worsening of renal function dependent on cyclosporin, or caused by acute renal insufficiency of postrenal origin, can be distinguished from viral infection and rejection reactions by the determination of interleukin-2 (IL-2) in plasma, which functions as an early indicator or follow-up parameter. A definite differentiation between steroid-sensitive rejection reactions and virus infection does not yet seem to be possible by interleukin-2 determination.
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