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[Breast cancer in men]
Summary
Male breast cancer is rare, often diagnosed late with symptoms like nipple changes and masses. Despite various treatments, prognosis remains poor, highlighting the need for further research and early detection strategies.
Area of Science:
- Oncology
- Urology
Context:
- Male breast cancer is a rare malignancy, accounting for less than 1.5% of all breast cancers.
- Typically affects men in their 7th and 8th decades of life.
Purpose:
- To present the clinical experience and outcomes of 16 male breast cancer patients.
- To review the diagnostic and therapeutic approaches for male breast carcinoma.
Summary:
- Common presenting symptoms include breast mass, nipple ulceration, retraction, or skin fixation.
- Ductal carcinoma is the most frequent histologic type.
- Early axillary lymph node involvement is common, and nipple discharge may indicate malignancy.
Impact:
- Standard surgical management for female breast cancer is generally applicable.
- Hormonal therapies (estrogens, androgens), orchiectomy, hypophysectomy, radiation, and chemotherapy have been employed.
- Despite therapeutic efforts, male breast carcinoma carries a serious prognosis.