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[Normal and impaired development of the ostium primum type atrial septal defect]
G Cabezuelo Huerta1, P Frontera Izquierdo
1Departamento de Pediatria, Hospital Infantil La Fe, Universidad de Valencía.
Insights
This study assessed outcomes for 48 children with atrial septal defect ostium primum, finding an 86.3% survival rate after surgical repair. Long-term follow-up revealed residual mitral regurgitation in most survivors.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Cardiac Surgery
Context:
- Atrial septal defect ostium primum (ASOPOP) is a specific type of congenital heart defect.
- This study retrospectively analyzed patients diagnosed between 1971-1988.
Purpose:
- To evaluate the long-term outcomes and survival rates of pediatric patients with ASOPOP.
- To assess the effectiveness of surgical repair for ASOPOP.
Summary:
- 48 patients with catheterization-proven ASOPOP were identified (2% of congenital heart disease diagnoses).
- 36 patients underwent surgical repair at a mean age of 6 years, with an 11.1% surgical mortality rate.
- Long-term follow-up (9 years average) in 32 survivors showed 2 with complete atrioventricular block requiring pacemakers and 26 with mild to moderate mitral regurgitation.
Impact:
- The study reports an overall actuarial survival rate of 86.3% at 10-15 years for ASOPOP patients.
- Surgically treated patients had an estimated 88.2% survival rate, highlighting the impact of intervention.
- Findings inform prognosis and management strategies for pediatric atrial septal defects.
Abstract:
We evaluate 48 patients who had catheterization-proved atrial septal defect ostium primum type. These patients are the 2% of the 2,322 children diagnosed of congenital heart disease by catheterization and angiography in our hospital at the 1971-1988 period. Of 48 children, 36 underwent corrective surgical repair at mean age of 6 years, with a surgical mortality rate of 11.1%. Our mortality rate total was 12.5% and the average follow-up was 9 years. The most recent evaluation in the 32 survivors of complete repair shows that 2 children had complete atrioventricular block and pacemaker implanted, and 26 children had residual mild to moderate mitral regurgitation. Two children are in the functional New York Heart Association class III and 24 children in the class I or II. The estimated actuarial survival rate at the 10-15 years is 86.3% in the total and 88.2% in the operated group.