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Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Related Experiment Video

Updated: May 15, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

SPECT/CT in sentinel node imaging.

Thomas Wagner1, John Buscombe, Gopinath Gnanasegaran

  • 1Department of Nuclear Medicine, Royal Free Hospital NHS, Trust, London, UK.

Nuclear Medicine Communications
|January 2, 2013
PubMed
Summary
This summary is machine-generated.

Single photon emission computed tomography/computed tomography (SPECT/CT) enhances sentinel lymph node imaging for cancer staging. This advanced technique offers superior anatomical localization and improved accuracy over planar imaging, aiding surgical decisions.

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Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
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Published on: October 20, 2010

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Last Updated: May 15, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

Area of Science:

  • Nuclear medicine
  • Oncology
  • Surgical oncology

Background:

  • Sentinel lymph node biopsy is standard for staging early breast cancer and melanoma.
  • Sentinel node lymphoscintigraphy is expanding to head and neck cancers and other solid tumors.

Purpose of the Study:

  • To review the potential application of single photon emission computed tomography/computed tomography (SPECT/CT) in sentinel node imaging.
  • To highlight the advantages of SPECT/CT over planar imaging for sentinel node assessment.

Main Methods:

  • Review of current literature and applications of SPECT/CT in sentinel node imaging.
  • Comparison of SPECT/CT performance against traditional planar lymphoscintigraphy.

Main Results:

  • SPECT/CT provides integrated functional and anatomical information, surpassing planar imaging in accuracy.
  • Advantages include precise anatomical localization, reduced false positives, and fewer false negatives.
  • SPECT/CT can alter surgical planning and improve sentinel node identification.

Conclusions:

  • SPECT/CT offers valuable pre-biopsy information for sentinel lymph node assessment.
  • The use of sentinel lymph node SPECT/CT is advocated for various tumors, including melanomas of the trunk and head and neck.