Related Experiment Video
Updated: May 15, 2026
10:38
Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
Published on: September 27, 2012
ROS signaling pathways and biological rhythms: perspectives in crustaceans.
1Departamento de Ecologia y Recursos Naturales, Facultad de Ciencias UNAM, Avenida Universidad 3000, Ciudad Universitaria, Mexico City 04510, Mexico. mfajul@gmail.com
Frontiers in Bioscience (Landmark Edition)
|January 2, 2013
Summary
This review explores the endogenous circadian clock, focusing on how oxidative stress (OS) and light influence its entrainment in crustaceans. It examines molecular mechanisms, redox signaling, and cryptochromes
Area of Science:
- Chronobiology
- Crustacean Biology
- Molecular Biology
Background:
- The endogenous circadian clock regulates physiological processes across diverse organisms.
- Oxidative stress (OS) and light are key environmental factors influencing circadian rhythm entrainment.
- Understanding these mechanisms in crustaceans, like crayfish, offers insights into invertebrate chronobiology.
Purpose of the Study:
- To review the molecular control of circadian rhythms in invertebrates, contrasting Drosophila models with crayfish.
- To examine the redox mechanisms and signaling pathways involved in circadian clock entrainment.
- To discuss light signals, cryptochromes (CRYs), and their potential roles in crustacean circadian and redox biology.
Main Methods:
- Literature review of circadian clock mechanisms in invertebrates.
- Comparative analysis of circadian genes and proteins in Drosophila and crayfish.
- Examination of redox signaling, light transduction pathways, and transcription factors (e.g., HIF-1 alpha).
Main Results:
- Circadian clock molecular control varies between invertebrates, with distinct gene/protein profiles in crayfish compared to Drosophila.
- Redox mechanisms and signaling pathways are integral to circadian clock entrainment.
- Cryptochromes (CRYs) play a dual role in circadian clocks, with potential links to redox mechanisms in crustaceans.
Conclusions:
- Circadian rhythms in crustaceans are influenced by OS and light, involving complex molecular and signaling pathways.
- Cryptochromes (CRYs) and transcription factors like HIF-1 alpha may be key regulators of circadian control genes (ccgs) in crustaceans.
- Further research is needed to fully elucidate the interplay between metabolism, ROS, and circadian regulation in crustaceans.
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