Related Experiment Video

Updated: May 15, 2026

Technique for Intranasal Administration of α-Synuclein Aggregates
04:49

Technique for Intranasal Administration of α-Synuclein Aggregates

Published on: November 8, 2024

Activity-dependent secretion of alpha-synuclein by enteric neurons

Sébastien Paillusson1, Thomas Clairembault, Mandy Biraud

  • 1Inserm, U913, Nantes, France.

Journal of Neurochemistry
|January 3, 2013
PubMed
Summary

Enteric neurons secrete alpha-synuclein, a protein implicated in Parkinson's disease (PD) spreading. This secretion occurs through a standard cellular process regulated by neuronal activity, offering new insights into PD's gastrointestinal origins.

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