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Updated: May 15, 2026

Measuring Psoriasis Severity at Home
Published on: March 1, 2024
Inflammatory arthritis following ustekinumab treatment for psoriasis: a report of two cases
A de Souza1, T Ali-Shaw, S M Reddy
1Department of Dermatology, New York University School of Medicine, New York, NY, USA. aieska@yahoo.com
Abstract:
Psoriasis is a chronic inflammatory skin condition, characterized by T-helper (Th) 1 and Th17 cell activation. Ustekinumab is a fully human immunoglobulin G1κ monoclonal antibody that targets the common p40 subunit that is shared by both interleukin (IL)-12 and IL-23, consequently inhibiting T-cell differentiation along both Th1 and Th17 pathways. This is a report of two patients who developed psoriatic arthritis during ustekinumab treatment for psoriasis. Neither patient had a personal or family history of arthritis.
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