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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
Proteinuria in canine patients with lymphoma
A Di Bella1, C Maurella, A Cauvin
1VRCC Veterinary Referrals, 1 Bramston Way, Southfield, Laindon, Essex.
The Journal of Small Animal Practice
|January 3, 2013
Summary
Proteinuria is common in dogs with lymphoma, affecting them more than healthy dogs. While often mild, this kidney condition is not linked to lymphoma stage.
Area of Science:
- Veterinary Medicine
- Canine Oncology
- Nephrology
Background:
- Lymphoma is a common cancer in dogs.
- Kidney involvement, including proteinuria, can occur in dogs with cancer.
- Understanding proteinuria in lymphoma patients is crucial for prognosis and management.
Purpose of the Study:
- To investigate the prevalence of proteinuria in dogs diagnosed with lymphoma.
- To compare proteinuria rates between dogs with lymphoma and healthy controls.
- To evaluate the severity and frequency of proteinuria in canine lymphoma cases.
Main Methods:
- A comparative study was conducted.
- Urine protein:creatinine ratio was measured in 32 dogs with lymphoma.
- The same ratio was measured in 30 healthy control dogs.
Main Results:
- Dogs with lymphoma exhibited a higher incidence of proteinuria compared to healthy dogs.
- Proteinuria was frequently observed in lymphoma patients, but typically mild in severity.
- No correlation was found between the presence of proteinuria and the stage or substage of lymphoma.
Conclusions:
- Mild proteinuria is a common clinical finding in canine lymphoma.
- The clinical significance and impact of this mild proteinuria are likely minimal.
- Routine monitoring for proteinuria may be beneficial in dogs with lymphoma.
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