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Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...

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Related Experiment Video

Updated: May 15, 2026

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

Asthma and obesity.

L-P Boulet1

  • 1Institut universitaire de cardiologie et de pneumologie de Québec, Laval University, Québec, QC, Canada. lpboulet@med.ulaval.ca

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
|January 3, 2013
PubMed
Summary
This summary is machine-generated.

Obesity is linked to increased asthma rates and makes asthma harder to control, potentially altering airway inflammation and reducing medication effectiveness. Weight loss can improve asthma outcomes in obese individuals.

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Related Experiment Videos

Last Updated: May 15, 2026

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

  • Pulmonology
  • Allergy and Immunology
  • Obesity Medicine

Background:

  • Asthma prevalence is rising, particularly in obese populations, suggesting a significant link.
  • Obesity is increasingly recognized as a risk factor for asthma development, though mechanisms remain unclear.
  • Existing hypotheses include genetic factors, altered lung mechanics, systemic inflammation, and comorbidities.

Purpose of the Study:

  • To explore the complex relationship between obesity and asthma.
  • To understand how obesity impacts asthma development, control, and treatment response.
  • To review current hypotheses and suggest future research directions.

Main Methods:

  • Review of existing literature and hypotheses on obesity and asthma.
  • Analysis of how obesity affects asthma diagnosis and control assessment.
  • Examination of potential changes in asthma phenotype and airway inflammation in obese individuals.

Main Results:

  • Obesity does not appear to lead to more frequent asthma over-diagnosis.
  • Obesity complicates asthma control and diminishes the efficacy of standard asthma medications.
  • Obese individuals may exhibit a less eosinophilic airway inflammation phenotype, alongside altered lung mechanics.

Conclusions:

  • Weight loss is associated with improved asthma control and should be a key component of management for obese asthma patients.
  • Further research is needed to elucidate obesity's influence on asthma's development, clinical presentation, and long-term outcomes.
  • Optimal asthma management strategies for obese individuals require further investigation.