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Updated: May 15, 2026

Murine Renal Transplantation Procedure
Published on: July 10, 2009
Expect the unexpected: pleuro-pulmonary melioidosis in a renal transplant recipient
1Department of Nephrology, Division of Medicine, Royal Darwin Hospital, Northern Territory Medical Program, Flinders University, Darwin, Northern Territory, Australia. Zulfikar.Jabbar@nt.gov.au
Abstract:
Melioidosis is an infectious disease endemic in tropical northern Australia and Southeast Asia, and, if treated late or inappropriately, is usually fatal. We report a rare case of pleuro-pulmonary melioidosis with septicemia in a renal transplant recipient to highlight the potential risk of acquiring this infection in at-risk patients living in, or visiting, regions that are endemic for melioidosis, and to convey the importance of its early diagnosis and specific treatment.
Insights
Melioidosis is a fatal infectious disease in endemic areas. Early diagnosis and treatment are crucial, especially for renal transplant recipients at risk.
Area of Science:
- Infectious Diseases
- Transplantation Immunology
Background:
- Melioidosis is a serious bacterial infection endemic in tropical regions.
- Late or inappropriate treatment leads to high mortality rates.
Observation:
- A rare case of pleuro-pulmonary melioidosis with septicemia occurred in a renal transplant recipient.
- This highlights infection risk for at-risk individuals in endemic zones.
Findings:
- The case underscores the importance of considering melioidosis in patients with relevant travel or residency history.
- Prompt and accurate diagnosis is vital for effective management.
Implications:
- Increased awareness of melioidosis risk in immunocompromised patients is needed.
- Early detection and specific antibiotic therapy can improve outcomes for this potentially fatal disease.
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