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Lead level in pregnant women suffering from pre-eclampsia in Dakahlia, Egypt
S M Motawei1, S M Attalla, H E Gouda
1Faculty of Medicine, Mansoura University, Egypt. sh-mm@mans.edu.eg
Background:
Lead toxicity is a prevalent health problem in both developed and developing countries. One of the proposed mechanisms for lead-induced organ damage is oxidative stress. Oxidative stress is well-associated with the pregnancy disorder, pre-eclampsia. Exposure to lead may be one of the sources of the oxidative stress that leads to development of pre-eclampsia in pregnant women.
Objective:
To test if blood lead level of pregnant women suffering from pre-eclampsia is higher than the normal limit.
Methods:
Using atomic absorption spectrophotometry, blood lead level was measured in 115 pregnant women suffering from pre-eclampsia and compared to its level in a comparison group of 25 healthy pregnant women in Dakahlia governorate, Egypt.
Results:
The mean±SD blood lead level was 37.68±9.17 μg/dL in women with pre-eclampsia; the value in the comparison group was 14.5±3.18 μg/dL (p<0.001).
Conclusion:
Pre-eclampsia is significantly associated with a high blood lead level.
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