Related Experiment Videos
C3 activation products correlate with antibodies to lipid A in pauciarticular juvenile arthritis
1Children's Hospital, Stanford, California 94304.
Arthritis and Rheumatism
|April 1, 1990
Abstract:
IgM antibodies to monophosphoryl-lipid A were found to be elevated in sera from children with all forms of juvenile arthritis (JA) and systemic lupus erythematosus. Of more interest, in patients with pauciarticular JA, IgG antibody titers to monophosphoryl-lipid A were found to be correlated with the C3a concentration and the C3d:C3 ratio. Although the full specificity of these antibodies is unknown, they are the first that have been found to be correlated with complement activation products in any form of JA.