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Updated: May 15, 2026

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
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Estrogenic effects along the river Saale.

Sebastian Buchinger1, Peter Heininger, Michael Schlüsener

  • 1Federal Institute of Hydrology, D-56068 Koblenz, Germany. buchinger@bafg.de

Environmental Toxicology and Chemistry
|January 3, 2013
PubMed
Summary

Sediments in the Saale River show high estrogenic activity, primarily from 4-nonylphenols. These xenoestrogens are a significant source of endocrine disruption in the Elbe River catchment area.

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Published on: January 1, 2018

Area of Science:

  • Environmental Chemistry
  • Ecotoxicology
  • Riverine Ecosystems

Background:

  • River Saale sediments, a tributary of the Elbe River, were investigated for endocrine-disrupting compounds.
  • Elevated estrogenic activity was detected, indicating potential contamination sources.

Purpose of the Study:

  • To identify sources of estrogenic activity in Saale River sediments.
  • To assess the contribution of specific compounds to endocrine disruption in the Elbe River system.

Main Methods:

  • Yeast estrogen screen (YES) was used to measure estrogenic activity.
  • Analysis of sediment extracts for 4-nonylphenols and natural steroidal estrogens.
  • Quantification of compounds and correlation with biological activity.

Main Results:

  • Estrogenic activity reached up to 55,000 ng ethinylestradiol equivalents/kg dry weight.
  • Maximal concentrations of 4-iso-nonylphenol (115 mg/kg) and estrone (20 µg/kg) were found at the Luppe sampling site.
  • 4-nonylphenols were identified as the primary contributors to the observed estrogenic effects.

Conclusions:

  • 4-nonylphenols are significant xenoestrogens in the Saale River catchment.
  • Sediment-associated 4-nonylphenol strongly correlates with estrogenic activity, highlighting its environmental relevance.
  • These findings are crucial for understanding and mitigating endocrine disruption in the Elbe River.