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Updated: May 15, 2026

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
Published on: October 22, 2015
Right frontal lobe glioma presenting as anorexia nervosa: further evidence implicating dorsal anterior cingulate as
Elizabeth Goddard1, Keyoumars Ashkan, Stuart Farrimond
1Section of Eating Disorders, Department of Psychological Medicine, King's College London, Institute of Psychiatry, London, United Kingdom.
Objective:
The association of anorexia nervosa (AN) with organic brain lesions may offer insight into underlying illness neuropathology. A systematic review reported an association between AN and lesions located in the right frontal lobe. To date, no studies have studied such a case longitudinally. A case of a male presenting with AN and a frontal lobe glioma is described.
Method:
The clinical symptoms and subsequent medical and neuropsychological investigations before and after surgery are reviewed.
Results:
The remission of ED symptoms is observed at 2 year post-surgery follow up.
Discussion:
The features of this case are set into the context of recent conceptualizations of AN and the clinical implications for identifying individuals with underlying organic causes.
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