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Published on: May 27, 2018
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Assembly of bacteriophage into functional materials.
Sung Ho Yang1, Woo-Jae Chung, Sean McFarland
1Department of Bioengineering, University of California, Berkeley, California 94720, USA.
Summary
Researchers are using self-templating methods to create ordered phage nanostructures for advanced materials. These ordered phage films exhibit unique optical properties, enabling new applications in sensing and biomaterial assembly.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Materials Engineering
Background:
- Phage (bacteriophage) fabrication into ordered structures is key for developing advanced materials.
- Phage are versatile building blocks for devices like batteries, solar cells, and sensors.
- Previous work focused on phage size for efficiency, not unique nanostructure properties.
Purpose of the Study:
- To explore self-templating methods for exploiting ordered phage nanostructures.
- To investigate novel functional properties of ordered phage films.
- To advance phage-based materials for sensing and biomacromolecule assembly studies.
Main Methods:
- Utilizing self-templating techniques to control deposition processes.
- Fabricating hierarchically organized phage architectures.
- Analyzing structural color and optical filtering in phage films.
Main Results:
- Self-templating methods enable exploitation of ordered phage structural properties.
- Ordered phage films display emergent functional properties like structural color and optical filtering.
- Phage films can be engineered for optical sensors by combining structural and binding properties.
Conclusions:
- Self-templating methods offer new routes for creating functional phage-based materials.
- Ordered phage nanostructures possess unique optical properties with potential in sensing.
- This approach provides insights into biomacromolecule assembly in complex systems.

