Related Experiment Video
Updated: May 15, 2026
09:07
A Human Bone Marrow 3D Model to Investigate the Dynamics and Interactions Between Resident Cells in Physiological or Tumoral Contexts
Published on: December 16, 2022
Replication of bone marrow differentiation niche: comparative evaluation of different three-dimensional matrices
Meghan J Cuddihy1, Yichun Wang, Charles Machi
1Department of Chemical Engineering, University of Michigan, 2300 Hayward Street, Ann Arbor, MI 48109, USA.
Small (Weinheim an Der Bergstrasse, Germany)
|January 3, 2013
Abstract:
The comparative evaluation of different 3D matrices-Matrigel, Puramatrix, and inverted colloidal crystal (ICC) scaffolds-provides a perspective for studying the pathology and potential cures for many blood and bone marrow diseases, and further proves the significance of 3D cultures with direct cell-cell contacts for in vitro mimicry of the human stem cell niche.
