Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Staphylococcal Skin Infections

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Subcutaneous Sweet Syndrome as an uncommon mucocutaneous manifestation in systemic lupus erythematosus: a case report and literature review.

Immunologic research·2026

Same author

Skin-Limited Neonatal Lupus in an Infant Conceived by In Vitro Fertilization and Surrogate Gestation.

Pediatric dermatology·2026

Same author

Reactive granulomatous dermatitis as a manifestation of primary vitreoretinal lymphoma.

JAAD case reports·2026

Same author

Possible immune reconstitution inflammatory syndrome due to Mycobacterium colombiense skin infection in a person living with HIV/AIDS.

Indian journal of dermatology, venereology and leprology·2025

Same author

[Lichen sclerosus induced by pembrolizumab].

Annales de pathologie·2025

Same author

Significance of Clinical-Pathological Correlation in Ponatinib Reactions.

Dermatology practical & conceptual·2025

Search research articles

Related Experiment Videos

[Cutaneous sarcoidosis. Case report].

Mónica Fernández-Sánchez¹, Marcela Saeb-Lima

¹Departamento de Dermatología y Dermatopatología, Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Secretaría de Salud, Distrito Federal, México. monica.fernandez@cieni.org.mx

Revista Medica Del Instituto Mexicano Del Seguro Social

|January 4, 2013

Summary

Sarcoidosis, a rare multisystemic disease, can present with unspecific skin lesions. Diagnosis requires identifying sarcoidal granulomas in multiple organs, even in rare cases like this Mexican patient.

Related Experiment Videos

Area of Science:

Immunology and Systemic Diseases
Dermatology and Granulomatous Disorders

Background:

Sarcoidosis is a multisystemic inflammatory disease characterized by non-caseating granulomas of unknown etiology.
Diagnosis involves demonstrating granulomas in at least two organs and excluding other conditions.
Skin involvement occurs in one-third of patients, and sarcoidosis is rare in Mexican populations.

Observation:

A 40-year-old female presented with a frontal scalp patch (hypopigmented, alopecic, atrophic with erythematous edge).
She also exhibited cough, dyspnea, neuropathy, and cardiac dysfunction.
Prior treatment for suspected pulmonary tuberculosis was noted.

Findings:

Lymph node and skin biopsies revealed the presence of sarcoidal granulomas.
The clinical presentation and biopsy findings confirmed sarcoidosis.
This case highlights sarcoidosis in a Mexican patient, a demographic rarely affected.

Implications:

Skin lesions in sarcoidosis can be nonspecific, underscoring the importance of biopsy.
Multisystemic involvement necessitates comprehensive diagnostic evaluation.
This case expands the understanding of sarcoidosis presentation in underrepresented populations.