Related Experiment Video
Updated: May 15, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Magnetic resonance imaging in perianal Crohn's disease
F Makowiec1, M Laniado, E C Jehle
1Departments of Surgery and *Diagnostic Radiology, Eberhard-Karls-University Tübingen, Germany.
Summary:
: Perianal Crohn's disease is frequently associated with complex fistulous tracts and deep abscesses which are often difficult to identify by clinical-proctological examination or anal endosonography. In a prospective study we examined the value of MRI in perianal Crohn's disease as compared to proctological and intraoperative findings. MRI of the perianal region was performed on 54 patients with active perianal Crohn's disease. Fistulas and abscesses were classified according to the anatomical region. The results were then compared with clinical and/or intraoperative findings. A total of 90 fistulas and 83 abscesses were found. MRI detected all abscesses and 82% of the fistulas. 30% of the abscesses and 26% of the fistulas were missed by clinical examination. MRI was less sensitive in detecting short transsphincteric fistulas, especially anovaginal fistulas. MRI is a painless procedure without radiation exposure. These features are important additional advantages in comparison to endosonography or CT. We believe MRI is the imaging method of choice in patients with active perianal Crohn's disease where the proctological examination including anal endosonography is inconclusive.
Related Concept Videos
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Magnetic Resonance Imaging
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Inflammatory Bowel Disease III: Crohn's Disease
Imaging Studies for Cardiovascular System IV: CMRI
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...

