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Related Experiment Video

Updated: May 15, 2026

Non-plasma Bonding of PDMS for Inexpensive Fabrication of Microfluidic Devices
04:45

Non-plasma Bonding of PDMS for Inexpensive Fabrication of Microfluidic Devices

Published on: November 1, 2007

Adhesive-based bonding technique for PDMS microfluidic devices.

C Shea Thompson1, Adam R Abate

  • 1UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco, San Francisco, California, USA.

Lab on a Chip
|January 4, 2013
PubMed
Summary
This summary is machine-generated.

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A simple, inexpensive method bonds polydimethylsiloxane (PDMS) microfluidic devices using only tape and an oven. This technique avoids plasma bonders and cleanrooms, enabling immediate hydrophobic channel formation for emulsion generation.

Area of Science:

  • Materials Science
  • Microfluidics
  • Chemical Engineering

Background:

  • Polydimethylsiloxane (PDMS) is a widely used material for microfluidic devices.
  • Traditional PDMS bonding methods often require specialized equipment like plasma bonders and cleanroom facilities.
  • These requirements increase the cost and complexity of microfluidic device fabrication.

Purpose of the Study:

  • To develop a simple, inexpensive, and accessible technique for bonding PDMS microfluidic devices.
  • To eliminate the need for plasma treatment and cleanroom environments.
  • To enable the rapid fabrication of hydrophobic microfluidic channels for specific applications.

Main Methods:

  • Utilizing adhesive tape as the primary bonding agent.
  • Employing a standard oven for thermal treatment.

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Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

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Microfluidic Synthesis of Microgel Building Blocks for Microporous Annealed Particle Scaffold
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Microfluidic Synthesis of Microgel Building Blocks for Microporous Annealed Particle Scaffold

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Related Experiment Videos

Last Updated: May 15, 2026

Non-plasma Bonding of PDMS for Inexpensive Fabrication of Microfluidic Devices
04:45

Non-plasma Bonding of PDMS for Inexpensive Fabrication of Microfluidic Devices

Published on: November 1, 2007

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices
04:54

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Published on: January 17, 2017

Microfluidic Synthesis of Microgel Building Blocks for Microporous Annealed Particle Scaffold
09:34

Microfluidic Synthesis of Microgel Building Blocks for Microporous Annealed Particle Scaffold

Published on: June 16, 2022

  • No plasma treatment or cleanroom facilities were used.

    • Main Results:

    • Successfully bonded PDMS microfluidic devices using only adhesive tape and an oven.
    • The developed technique is cost-effective and does not require specialized equipment.
    • The bonded channels exhibited immediate hydrophobicity, suitable for direct use.

    Conclusions:

    • The proposed tape-assisted thermal bonding is a viable and economical alternative for PDMS microfluidic device fabrication.
    • This method democratizes microfluidic device creation by removing accessibility barriers.
    • The inherent hydrophobicity of the resulting channels facilitates applications such as aqueous-in-oil emulsion formation.