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Updated: May 15, 2026

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
Published on: January 27, 2018
Acute cervical dystonia after the first dose of butamirate citrate
Erhan Bayram1, Pakize Karakaya, Yasemin Topcu
1Division of Pediatric Neurology, Department of Pediatric Neurology, Dokuz Eylul University Medicine Faculty, Izmir, Turkey. dr.erhanbayram@yahoo.com
Abstract:
Butamirate citrate is a central-acting antitussive drug and is widely used in clinical practice in childhood. It is thought that to be centrally active antitussive drugs act through receptors in the brainstem to inhibit cough, and these findings were based on the evidence of animal models. Central nervous system adverse effects of cough suppressants are rare and include irritability, lethargy, hallucinations, and dystonic reactions. In this report, we present the first patient who developed cervical dystonia shortly after the first dose of butamirate citrate, and the patient's symptoms improved immediately after a single intramuscular dosage of biperiden.
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