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Updated: May 15, 2026
11:45
Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
2-Cyano-N'-[1-(pyridin-2-yl)ethyl-idene]acetohydrazide
Xiao-Yi Zhang1, Xiao-Lin Han, Zhi-Bin Qian
1School of Pharmacy, Xinxiang Medical University, Xinxiang Henan 453003, People's Republic of China.
Acta Crystallographica. Section E, Structure Reports Online
|January 4, 2013
Summary
This study details the molecular structure of a novel pyridine derivative, C(10)H(10)N(4)O. The research highlights the specific dihedral angle and hydrogen bonding interactions within its crystal structure.
Area of Science:
- Crystallography
- Organic Chemistry
- Molecular Structure
Background:
- Pyridine derivatives are important in medicinal chemistry and materials science.
- Understanding molecular conformation and intermolecular interactions is crucial for predicting compound properties.
Purpose of the Study:
- To elucidate the crystal structure and molecular geometry of the title compound, C(10)H(10)N(4)O.
- To investigate the intermolecular interactions, specifically hydrogen bonding, in the solid state.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the three-dimensional structure.
- Analysis of bond lengths, bond angles, and dihedral angles provided detailed geometric information.
- Hydrogen bonding networks were identified and characterized.
Main Results:
- The dihedral angle between the pyridine ring and the -C=O(CH(2))CN group was determined to be 24.08(12)°.
- Inversion dimers were observed in the crystal lattice.
- Pairs of N-H⋯N hydrogen bonds were identified, forming R(2)(2)(8) loops.
Conclusions:
- The study provides a precise description of the molecular conformation and crystal packing of C(10)H(10)N(4)O.
- The identified hydrogen bonding pattern influences the overall crystal structure and stability.
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