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Updated: May 15, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
5-(Diphenyl-methyl-idene)pyrrolidin-2-one.
Tzu-Fang Hsu1, Yan-Ru Chen, Bor-Hunn Huang
1Department of Applied Cosmetology and Graduate Institute of Cosmetic Science, Hungkuang University, Taichung 433, Taiwan.
This study details the crystal structure of a novel organic compound, C(17)H(15)NO. Molecules form dimers through hydrogen bonds, revealing specific molecular arrangements in the solid state.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding molecular interactions is crucial in chemistry.
- Crystal engineering utilizes intermolecular forces to design materials.
- Dihedral angles and hydrogen bonding dictate crystal packing.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(17)H(15)NO.
- To analyze the intermolecular interactions, specifically hydrogen bonding and phenyl ring orientation.
- To characterize the supramolecular assembly in the solid state.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and dihedral angles.
- Identification and analysis of hydrogen bonding networks and other non-covalent interactions.
Main Results:
- The crystal structure of C(17)H(15)NO was successfully determined.
- A significant dihedral angle of 80.1(2)° was observed between the phenyl rings.
- Molecules are organized into inversion dimers via N-H⋯O hydrogen bonds.
Conclusions:
- The crystal packing is governed by specific N-H⋯O hydrogen bonding interactions.
- The observed dihedral angle influences the overall molecular conformation and crystal packing.
- The formation of inversion dimers is a key feature of the supramolecular architecture.
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