Global effect of inauhzin on human p53-responsive transcriptome

Jun-Ming Liao1, Shelya X Zeng, Xiang Zhou

  • 1Department of Biochemistry & Molecular Biology and Tulane Cancer Center, Tulane University School of Medicine, New Orleans, Louisiana, USA.

Plos One
|January 4, 2013
PubMed
Summary

Inauhzin (INZ) globally impacts the p53-responsive transcriptome, activating numerous p53 target genes involved in critical cellular processes like apoptosis and cell cycle regulation. This study identifies potential novel p53 targets and informs future Inauhzin clinical trials.

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