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Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Blood Flow01:29

Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models00:57

Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models

Physiological pharmacokinetic models, often called flow-limited or perfusion models, typically assume a swift drug distribution between tissue and venous blood, creating a rapid drug equilibrium. This premise is based on the idea that drug diffusion is extremely fast, and the cell membrane presents no barrier to drug permeation. In this scenario, where no drug binding occurs, the drug concentration in the tissue equals that of the venous blood leaving the tissue. This greatly simplifies the...
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.
Assessing Blood pressure using a doppler ultrasound01:19

Assessing Blood pressure using a doppler ultrasound

To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:

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Related Experiment Video

Updated: May 15, 2026

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
07:13

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

[A study on blood flow measurement by diffuse correlation spectroscopy].

Jia-Ming Liang1, Jing Wang, Jian-Sheng Mei

  • 1The Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Biomedical Analytical Technology and Instrumentation, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China. ljm1220@163.com

Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu
|January 5, 2013
PubMed
Summary
This summary is machine-generated.

This study introduces a noninvasive method using near-infrared diffuse correlation spectroscopy (DCS) to measure blood flow. The developed system accurately assesses forearm blood flow, demonstrating feasibility for clinical applications.

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Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
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Last Updated: May 15, 2026

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
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Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
11:39

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Published on: March 14, 2013

Area of Science:

  • Biomedical Optics
  • Physiological Measurement
  • Photonics in Medicine

Context:

  • Accurate blood flow measurement is crucial for clinical diagnosis and treatment.
  • Noninvasive techniques are highly desired by clinicians and patients.
  • Existing methods may be invasive or lack depth profiling capabilities.

Purpose:

  • To develop and validate a noninvasive method for measuring blood flow.
  • To theoretically analyze the relationship between light scattering and blood flow.
  • To build a functional system for real-time blood flow assessment.

Summary:

  • Near-infrared diffuse correlation spectroscopy (DCS) was employed to measure blood flow noninvasively.
  • A theoretical model and measurement system were established, analyzing speckle intensity fluctuations.
  • Forearm blood flow was measured in human subjects during cuff inflation/deflation, confirming system feasibility.

Impact:

  • Demonstrates the feasibility of noninvasive blood flow measurement using DCS.
  • Suggests the potential for depth-resolved blood flow information within tissues.
  • Paves the way for improved noninvasive hemodynamic monitoring in clinical settings.