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[Dengzhanxixin injection using character analysis in clinical based on real world HIS database]
Wei Yang1, Hao Cheng, Yan-Ming Xie
1Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. ywonline@163.com
Summary
Dengzhanxixin injection is primarily used for patients over 45, often for ischemic stroke, heart disease, diabetes, and hypertension. Clinical use, including dosage and duration, generally aligns with established guidelines.
Area of Science:
- Traditional Chinese Medicine
- Pharmacology
- Clinical Practice
Background:
- Dengzhanxixin injection is a component of Traditional Chinese Medicine.
- Understanding its clinical application is crucial for optimizing patient outcomes.
- Standardizing its use can inform future research and clinical guidelines.
Purpose of the Study:
- To investigate the current clinical usage patterns of Dengzhanxixin injection.
- To provide data for regulating its clinical application.
- To guide the design of prospective studies on Dengzhanxixin injection.
Main Methods:
- Retrospective analysis of 20 comprehensive hospital information system (HIS) databases.
- Data cleaning and patient information extraction for Dengzhanxixin injection users.
- Application of descriptive statistics and association rule analysis.
Main Results:
- The primary patient demographic is individuals over 45 years old.
- Commonly treated conditions include ischemic stroke, coronary heart disease, diabetes, and hypertension.
- Intravenous administration is the standard route, typically 30-40 mL daily for 14 days.
Conclusions:
- Dengzhanxixin injection is predominantly used in elderly patients.
- Clinical application largely adheres to product instructions.
- Comorbidities such as diabetes and hypertension are frequent in patients receiving Dengzhanxixin injection.