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[Literature review report on efficacy evaluation about Kudiezi injection]
Xing Liao1, Hao Shen, Yan-Ming Xie
1Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. okfrom2008@hotmail.com
Objective:
To explore information about label use and off label use about Kudeizi injection in clinical practice.
Method:
Three Chinese literature databases were searched and 237 articles were downloaded. Efficacy evaluation information about the study question was extracted by researchers in the Excel form. Finally, 3 systematic reviews and 190 RCTs, 20 clinical controlled trials, 21 case series and 3 case reports were identified. It only did an overview on three systematic reviews and 190 RCTs.
Result:
It is found that the most common disease treated by Kudiezi injection were cerebral infarction, coronary heart disease and angina pectoris. There are also many off label use about Kudiezi injection.
Conclusion:
Although there are more or less quality problems for these clinical trials of Kudiezi injection, researchers have already made effort to improve trials. There will be still a long way to develop good clinical trials for Kudiezi injection.
