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Updated: May 15, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Published on: March 15, 2019
Caffeine ingestion and intense resistance training minimize postexercise hypotension in normotensive and
Todd Anthony Astorino1, Brian J Martin, Lena Schachtsiek
1CSU-San Marcos, Kinesiology, San Marcos, California, USA. astorino@csusm.edu
Abstract:
The primary aim of the study was to compare changes in blood pressure (BP) in normotensive and prehypertensive men completing resistance exercise following caffeine ingestion. Normotensive (n = 7) and hypertensive men (n = 7) ingested caffeine (6 mg x kg(-1)) or placebo 1 h preexercise, then completed four sets of bench press, leg press, lat pull-down, and shoulder press at 70%-80% one repetition maximum (1-RM). Heart rate (HR) and BP were measured preexercise, during exercise, and for 75 min postexercise. Caffeine increased (p < 0.05) resting, exercise, and recovery systolic BP, yet had no effect on HR (p = 0.16) or diastolic BP (p = 0.10). HR and BP were significantly higher (p < 0.05) in prehypertensive men versus normotensives. Postexercise hypotension did not occur in either treatment, suggesting that intense resistance training with or without caffeine intake may mitigate the BP-lowering effect of resistance exercise.
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