Related Experiment Video
Updated: May 15, 2026

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
Published on: March 19, 2016
When blood is thinner than water
Dilip Gude1, Aslam Abbas, Hina Mohiuddin
1Department of Internal Medicine, Princess Durru Shehvar Children's and General Hospital, Purani Haveli, Hyderabad, India.
Abstract:
Antagonists of vitamin K dependant clotting factors are commonly used as treatment/prophylaxis for anticoagulation. Due to their narrow therapeutic window, a wide range of complications including death may occur. International normalized ratio (INR) is monitored to measure adequacy/excess of anticoagulation. There is a plethora of risk factors that may contribute to the uncontrollably high INR values. We describe our experience of a case of deep venous thrombosis wherein the patient had an overshoot of INR during anticoagulation therapy. We review the literature and discuss management in such scenarios.
Related Concept Videos
Characteristics and Functions of Blood
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...
Anatomy of the Circulatory System
Fluid Connective Tissues: Blood and Lymph
Blood
The blood flows through blood vessels— arteries, capillaries, and veins. Blood plasma is primarily made of proteins, solutes, and water.
Blood Flow
Capillary Exchange
Structure of Blood Vessels

