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Updated: May 15, 2026

Surgical Technique for Superior Cervical Ganglionectomy in a Murine Model
Published on: December 2, 2022
The C2 ganglion sectioning epidural approach to craniocervical junction chordoma: a technical case report
Naoshi Hagihara1, Toshio Matsushima, Masatou Kawashima
1Department of Neurosurgery, Saga University, Saga, Japan. naoshi.hagihara@gmail.com
Abstract:
In chordoma, complete surgical removal of the epidural tumor should be the first choice of treatment. Numerous surgical approaches to clival chordoma have been described: anterior approaches, lateral approaches, and posterolateral approaches. A multistaged operation with a combination of these approaches is generally performed. We used three approaches to remove a clival chordoma extending from the lower clivus anteriorly to the anterior perivertebral space and inferiorly to the C2 level. The epidural posterolateral approach through the vertebral artery (VA)-C2 interval space after resection of the C2 dorsal ganglion was the most effective. To our knowledge, the epidural posterolateral approach below VA, referred to as C2 ganglion sectioning epidural approach has not been reported as an independent approach in detail. We report a two-year-old girl with a lower clival chordoma which has been excised using C2 ganglion sectioning epidural approach.
