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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

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Published on: July 28, 2013

Diffusion tensor imaging of normal brain development.

Shoko Yoshida1, Kenichi Oishi, Andreia V Faria

  • 1The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 210 Traylor Building, 720 Rutland Ave., Baltimore, MD 21205, USA.

Pediatric Radiology
|January 5, 2013
PubMed
Summary
This summary is machine-generated.

Diffusion tensor imaging (DTI) offers insights into pediatric brain development and white matter maturation. This review covers DTI

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Area of Science:

  • Neuroimaging
  • Developmental Neuroscience
  • Biomedical Engineering

Background:

  • Diffusion tensor imaging (DTI) is a magnetic resonance imaging (MRI) technique.
  • DTI measures macroscopic structural organization in brain tissues.
  • It provides information complementary to relaxation-based MRI on brain microstructure changes.

Purpose of the Study:

  • To review the advantages and technical pitfalls of pediatric DTI.
  • To discuss image quantification strategies for DTI-derived parameters.
  • To outline normal brain developmental changes in these parameters.

Main Methods:

  • Review of existing literature on pediatric DTI.
  • Discussion of DTI technical aspects and limitations in children.
  • Exploration of quantification methods for DTI parameters.

Main Results:

  • DTI enables quantitative observation of white matter maturation in pediatric populations.
  • It effectively delineates brain structures during development.
  • Normal developmental changes in DTI parameters are discussed.

Conclusions:

  • Pediatric DTI is a valuable tool for characterizing normal and abnormal brain anatomy.
  • Understanding DTI advantages, pitfalls, and developmental changes is crucial for its application.
  • Further research can refine DTI applications in pediatric neurodevelopment.