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Related Experiment Video

Updated: May 15, 2026

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis
07:06

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis

Published on: July 6, 2022

Meniscal allograft shrinkage-MRI evaluation.

Thomas Carter1, Kostas John Economopoulos

  • 1Department of Orthopaedics, The Orthopaedic Clinic Association, Phoenix, Arizona 85016, USA. tcarter@tocamd.com

The Journal of Knee Surgery
|January 5, 2013
PubMed
Summary

Meniscal allograft transplantation (MAT) commonly results in graft shrinkage, averaging 7%. A significant portion of patients (32%) experienced 10% or greater shrinkage following this knee surgery.

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Area of Science:

  • Orthopedic surgery
  • Biomedical engineering
  • Regenerative medicine

Background:

  • Meniscal allograft transplantation (MAT) is an effective treatment for knees lacking menisci.
  • Previous studies noted meniscal graft shrinkage, but quantification was lacking.

Purpose of the Study:

  • To quantify the frequency and degree of meniscal shrinkage after transplantation.
  • To assess meniscal volume changes post-MAT.

Main Methods:

  • Prospective study of 25 patients undergoing MAT.
  • MR scans and 3-D coordinate digitizing system (3-DCDS) used to measure meniscal volume at 1 and 6 months post-surgery.

Main Results:

  • Average meniscal shrinkage was 7% (range 0-22%).

Related Experiment Videos

Last Updated: May 15, 2026

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis
07:06

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis

Published on: July 6, 2022

  • 68% of grafts showed at least 5% shrinkage.
  • 32% of grafts exhibited 10% or greater shrinkage.

    • Conclusions:

    • Meniscal allograft shrinkage is a frequent occurrence after transplantation.
    • The average shrinkage is 7%, with a notable percentage experiencing substantial shrinkage.