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Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
Published on: October 4, 2019
Evaluation of the packaging and encapsulation reliability in fully integrated, fully wireless 100 channel Utah Slant
A Sharma1, L Rieth, P Tathireddy
1Dept. of Electrical and Computer Engineering, Univ. of Utah, Salt Lake City, Utah, 84112, USA.
Summary
This study assessed the reliability of a wireless neural interface, the Utah Slant Electrode Array/integrated neural interface-recording version 5 (USEA/INI-R5). The device demonstrated stable function and recording capabilities after 12 months of immersion, indicating its suitability for chronic implants.
Area of Science:
- Biomedical Engineering
- Neurotechnology
- Materials Science
Background:
- Reliable neural interfaces are crucial for advanced neuroprosthetics and research.
- Encapsulation integrity is a key challenge for long-term in-vivo performance of implantable devices.
Purpose of the Study:
- To evaluate the encapsulation and packaging reliability of a fully integrated, wireless 100-channel Utah Slant Electrode Array/integrated neural interface-recording version 5 (USEA/INI-R5).
- To assess the long-term in-vitro functional stability and recording longevity of the wireless neural interface.
Main Methods:
- The USEA/INI-R5, encapsulated with 6-micrometer Parylene-C, was immersed in phosphate-buffered saline (PBS) for over 12 months at room temperature.
- Wireless power and configuration were achieved via a 2.765 MHz inductive link.
- Radio-frequency (RF) signals (900 MHz ISM band) were transmitted using frequency shift keying (FSK) and recorded wirelessly.
- In-vitro wireless recording in agarose was performed to test long-term recording ability.
Main Results:
- The USEA/INI-R5 maintained full functionality after 12 months of PBS immersion.
- Electrodes retained the ability to record artificial neural signals post-soak.
- Wireless communication and power remained stable throughout the testing period.
Conclusions:
- The 12-month PBS soak demonstrates the high encapsulation reliability of the USEA/INI-R5.
- The wireless neural interface exhibits excellent functional and recording stability.
- These findings suggest significant potential for the USEA/INI-R5 in future chronic implant applications.

