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A primary map of 24 loci on human chromosome 16
C Julier1, Y Nakamura, M Lathrop
1Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City 84132.
Genomics
|March 1, 1990
Abstract:
A primary genetic map of chromosome 16 has been constructed by linkage analysis of 24 polymorphic loci, typed in 59 reference families. These loci form a continuous map that covers the whole chromosome and spans genetic distances of 187 cM in males and 226 cM in females. Most of the sex-specific recombination rate difference comes from a nontelomeric region that covers 10 cM in males and 74 cM in females. Both telomeric regions show the opposite trend, with a significant increase in the male recombination rate.