Cutaneous and leptomeningeal hemangiomas with impressive benign evolution

Area of Science:

• Neurology
• Pediatrics
• Dermatology

Background:

• Pascual-Castroviejo type II syndrome is a rare neurological disorder.
• It is characterized by specific vascular malformations in infants.

Observation:

• An infant presented with congenital cutaneous and leptomeningeal hemangiomas.
• Imaging confirmed diffuse vascular lesions in the brain's meninges.
• Facial anomalies were noted at birth.

Findings:

• The infant's hemangiomas showed rapid, spontaneous resolution within one year.
• The patient lacked typical features such as persistent embryonic arteries or posterior fossa malformations.
• Diagnosis of a benign spectrum of Pascual-Castroviejo II syndrome was made.

Implications:

• This case expands the understanding of Pascual-Castroviejo II syndrome's clinical spectrum.
• Highlights the importance of recognizing benign variants with favorable prognoses.
• Suggests that rapid involution may be a key indicator in diagnosing milder forms.