Related Experiment Video
Updated: May 15, 2026
Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
Highly selective fluorescence turn-on chemosensor based on naphthalimide derivatives for detection of copper(II) ions
Zhijun Chen1, Limin Wang, Gang Zou
1Shanghai Key Laboratory of Functional Materials Chemistry and Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, PR China.
Abstract:
A new fluorescent probe, DN-SB, was synthesized. DN-SB was based on the naphthalimide derivatives and exhibited high selectivity and sensitivity for Cu(2+) ions. As a Cu(2+)-amplified fluorescent probe, its fluorescence spectrum showed 4.5-fold enhancement in the intensity of the signal at 519 nm on binding with the Cu(2+). Based on the fluorescence titration spectra and job's-plot, binding mode of DN-SB with Cu(2+) was proposed. Fluorescence intensity was linear with concentration of Cu(2+) cation in a range from 4 μM to 7 μM. DN-SB was also sensitive for copper ions. The detection limit was calculated to be 0.15 μM which indicated DN-SB was sensitive to Cu(2+).
