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High-performance liquid chromatographic assay of iomeprol in plasma and urine
V Lorusso1, I Poggesi, D Dal Fiume
1Bracco Research Department, Milan, Italy.
Journal of Chromatography
|February 23, 1990
Abstract:
A high-performance liquid chromatographic method for assaying the radiographic contrast agent iomeprol in plasma and urine samples is described. Before reversed-phase chromatography, the biological fluids are treated with ion-exchange resins and iopamidol is added as internal standard. The compounds are monitored during elution by ultraviolet-visible spectrometry at 245 nm. The method shows good precision and accuracy and gives similar results to X-ray fluorescence analysis.